Use this calculator as a guide to help determine your patient's weight-based dose of ACTEMRA

Select Patient Indication:

Enter Patient Weight:


Select Dosage Amount:

Recommended SJIA dosage every 2 weeks

Patients <30 kg - 12 mg/kg

Patients ≥30 kg - 8 mg/kg

Recommended PJIA dosage every 4 weeks

Patients <30 kg - 10 mg/kg

Patients ≥30 kg - 8 mg/kg

80 mg 4 mL

200 mg 10 mL

400 mg 20 mL

DISCLAIMER: By using this resource, you agree to the following: This Dosing Calculator is being provided "AS IS" and is intended for use only by qualified healthcare providers. All calculations should be confirmed before use. Genentech makes no claims as to the accuracy of the information contained herein. The information being provided is not a substitute for clinical judgment. Neither Genentech, nor any other party involved in the preparation or publication of this site, shall be liable to you or others for any decisions made or actions taken by you or others in reliance on this information. ACTEMRA should not be infused concomitantly in the same intravenous line with other drugs. No physical or biochemical compatibility studies have been conducted to evaluate the co-administration of ACTEMRA with other drugs. The infusion should be administered over 60 minutes, and must be administered with an infusion set. Do not administer as an intravenous push or bolus. Dosing Calculator should not replace professional judgment or clinical experience. For additional dosing information please refer to the Dosing Guide. Doses exceeding 800 mg per infusion are not recommended. Dosing Calculator is not a substitute for medical examination. The recommended starting dose of ACTEMRA SC for patients ≥100 kg is 162 mg administered subcutaneously every week. The recommended starting dose for ACTEMRA IV for adult patients is 4 mg/kg every 4 weeks followed by an increase to 8 mg/kg every 4 weeks based on clinical response.