Rheumatoid Arthritis Mechanism of Action
ACTEMRA: Designed to specifically target and inhibit IL-6 signaling
Proposed pharmacodynamic effects of IL-6 signaling inhibition30-34

 

Changes in pharmacodynamic parameters do not necessarily reflect a separate and distinct clinical benefit.

ESR=erythrocyte sedimentation rate; Hb=hemoglobin; IL-6=interleukin-6; RF=rheumatoid factor.

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